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THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT
1. Heat does not sensitize paramecia to ultraviolet light but ultraviolet light sensitizes them to heat. Paramecia of two species (Paramecium caudatum and P. multimicronucleate) are much more readily killed by heat at 42.3° C. if they are first exposed to ultraviolet light. 2. From studies on parame...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1945
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142730/ https://www.ncbi.nlm.nih.gov/pubmed/19873447 |
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author | Giese, Arthur C. Crossman, Elizabeth B. |
author_facet | Giese, Arthur C. Crossman, Elizabeth B. |
author_sort | Giese, Arthur C. |
collection | PubMed |
description | 1. Heat does not sensitize paramecia to ultraviolet light but ultraviolet light sensitizes them to heat. Paramecia of two species (Paramecium caudatum and P. multimicronucleate) are much more readily killed by heat at 42.3° C. if they are first exposed to ultraviolet light. 2. From studies on paramecia irradiated with a given dosage at various wave lengths before being killed by heat, an action spectrum of the compound in the protoplasm being sensitized to heat can be determined. Proteins with absorption similar to that of pseudoglobulin are suggested by these experiments. 3. The effect upon living things differs from that on pure protein systems in that paramecia are not rendered more sensitive to temperatures below the lethal temperature whereas proteins are. 4. Almost complete recovery from ultraviolet light as judged by heat sensitivity occurs within 4 to 5 days. 5. By a study of the rate of recovery from doses at different wave lengths evidence suggesting effects on nucleic acid is obtained. 6. The possible significance of the data and the action spectrum is discussed. |
format | Text |
id | pubmed-2142730 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1945 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21427302008-04-23 THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT Giese, Arthur C. Crossman, Elizabeth B. J Gen Physiol Article 1. Heat does not sensitize paramecia to ultraviolet light but ultraviolet light sensitizes them to heat. Paramecia of two species (Paramecium caudatum and P. multimicronucleate) are much more readily killed by heat at 42.3° C. if they are first exposed to ultraviolet light. 2. From studies on paramecia irradiated with a given dosage at various wave lengths before being killed by heat, an action spectrum of the compound in the protoplasm being sensitized to heat can be determined. Proteins with absorption similar to that of pseudoglobulin are suggested by these experiments. 3. The effect upon living things differs from that on pure protein systems in that paramecia are not rendered more sensitive to temperatures below the lethal temperature whereas proteins are. 4. Almost complete recovery from ultraviolet light as judged by heat sensitivity occurs within 4 to 5 days. 5. By a study of the rate of recovery from doses at different wave lengths evidence suggesting effects on nucleic acid is obtained. 6. The possible significance of the data and the action spectrum is discussed. The Rockefeller University Press 1945-11-20 /pmc/articles/PMC2142730/ /pubmed/19873447 Text en Copyright © Copyright, 1945, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Giese, Arthur C. Crossman, Elizabeth B. THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT |
title | THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT |
title_full | THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT |
title_fullStr | THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT |
title_full_unstemmed | THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT |
title_short | THE ACTION SPECTRUM OF SENSITIZATION TO HEAT WITH ULTRAVIOLET LIGHT |
title_sort | action spectrum of sensitization to heat with ultraviolet light |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142730/ https://www.ncbi.nlm.nih.gov/pubmed/19873447 |
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