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ON THE NATURE OF FORCES OPERATING IN BLOOD CLOTTING : II. THE CLOTTING OF FIBRINOGEN AS A TWO-STEP REACTION
It is found that clotting of fibrinogen by thrombin does not occur on the acid side of the isoelectric point of the fibrinogen. At such pH values, however, a primary reaction between thrombin and fibrinogen takes place, leading to the formation of profibrin, a compound of thrombin and fibrinogen. At...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
1945
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142733/ https://www.ncbi.nlm.nih.gov/pubmed/19873444 |