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Structural Requirements for Yersinia YopJ Inhibition of MAP Kinase Pathways

MAPK signaling cascades are evolutionally conserved. The bacterial effector, YopJ, uses the unique activity of Ser/Thr acetylation to inhibit the activation of the MAPK kinase (MKK) and prevent activation by phosphorylation. YopJ is also able to block yeast MAPK signaling pathways using this mechani...

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Detalles Bibliográficos
Autores principales:	Hao, Yi-Heng, Wang, Yong, Burdette, Dara, Mukherjee, Sohini, Keitany, Gladys, Goldsmith, Elizabeth, Orth, Kim
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147050/ https://www.ncbi.nlm.nih.gov/pubmed/18167536 http://dx.doi.org/10.1371/journal.pone.0001375

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