Cargando…
Sterile Protection against Malaria Is Independent of Immune Responses to the Circumsporozoite Protein
BACKGROUND: Research aimed at developing vaccines against infectious diseases generally seeks to induce robust immune responses to immunodominant antigens. This approach has led to a number of efficient bacterial and viral vaccines, but it has yet to do so for parasitic pathogens. For malaria, a dis...
Autores principales: | Grüner, Anne Charlotte, Mauduit, Marjorie, Tewari, Rita, Romero, Jackeline F., Depinay, Nadya, Kayibanda, Michèle, Lallemand, Eliette, Chavatte, Jean-Marc, Crisanti, Andrea, Sinnis, Photini, Mazier, Dominique, Corradin, Giampietro, Snounou, Georges, Rénia, Laurent |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147056/ https://www.ncbi.nlm.nih.gov/pubmed/18159254 http://dx.doi.org/10.1371/journal.pone.0001371 |
Ejemplares similares
-
A Role for Immune Responses against Non-CS Components in the Cross-Species Protection Induced by Immunization with Irradiated Malaria Sporozoites
por: Mauduit, Marjorie, et al.
Publicado: (2009) -
Inhibitory Effect of TNF-α on Malaria Pre-Erythrocytic Stage Development: Influence of Host Hepatocyte/Parasite Combinations
por: Depinay, Nadya, et al.
Publicado: (2011) -
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host
por: Coppi, Alida, et al.
Publicado: (2011) -
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion
por: Coppi, Alida, et al.
Publicado: (2005) -
Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria
por: Obeid, Michel, et al.
Publicado: (2013)