SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA

1. The motility and metabolism of human spermatozoa are inhibited by substances which have an affinity for sulfhydryl groups. 2. These inhibitions can be prevented, and in part, reversed, by the addition to the cell + inhibitor system of sulfhydryl compounds such as cysteine or glutathione. 3. Cyste...

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Detalles Bibliográficos
Autor principal: MacLeod, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1951
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147277/
https://www.ncbi.nlm.nih.gov/pubmed/14832448
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author MacLeod, John
author_facet MacLeod, John
author_sort MacLeod, John
collection PubMed
description 1. The motility and metabolism of human spermatozoa are inhibited by substances which have an affinity for sulfhydryl groups. 2. These inhibitions can be prevented, and in part, reversed, by the addition to the cell + inhibitor system of sulfhydryl compounds such as cysteine or glutathione. 3. Cysteine and glutathione, under aerobic conditions or in a system in which these substances can be oxidized, show widely different effects on the motility of the spermatozoa. Cysteine destroys the motility of the spermatozoa, whereas glutathione has no effect upon it. 4. Possible mechanisms of these effects are discussed.
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spelling pubmed-21472772008-04-23 SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA MacLeod, John J Gen Physiol Article 1. The motility and metabolism of human spermatozoa are inhibited by substances which have an affinity for sulfhydryl groups. 2. These inhibitions can be prevented, and in part, reversed, by the addition to the cell + inhibitor system of sulfhydryl compounds such as cysteine or glutathione. 3. Cysteine and glutathione, under aerobic conditions or in a system in which these substances can be oxidized, show widely different effects on the motility of the spermatozoa. Cysteine destroys the motility of the spermatozoa, whereas glutathione has no effect upon it. 4. Possible mechanisms of these effects are discussed. The Rockefeller University Press 1951-05-20 /pmc/articles/PMC2147277/ /pubmed/14832448 Text en Copyright © Copyright, 1951, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
MacLeod, John
SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA
title SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA
title_full SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA
title_fullStr SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA
title_full_unstemmed SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA
title_short SULFHYDRYL GROUPS IN RELATION TO THE METABOLISM AND MOTILITY OF HUMAN SPERMATOZOA
title_sort sulfhydryl groups in relation to the metabolism and motility of human spermatozoa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147277/
https://www.ncbi.nlm.nih.gov/pubmed/14832448
work_keys_str_mv AT macleodjohn sulfhydrylgroupsinrelationtothemetabolismandmotilityofhumanspermatozoa

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