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THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE
1. It has been shown that a number of proteolytic enzymes and snake venom, in relatively small amounts, and within a wide range of pH variation, will restore hyaluronidase activity after its inhibition by serum. 2. The known properties of the venom protease are found to be identical with those of Ha...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1953
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147353/ https://www.ncbi.nlm.nih.gov/pubmed/13022932 |
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author | Hadidian, Z. |
author_facet | Hadidian, Z. |
author_sort | Hadidian, Z. |
collection | PubMed |
description | 1. It has been shown that a number of proteolytic enzymes and snake venom, in relatively small amounts, and within a wide range of pH variation, will restore hyaluronidase activity after its inhibition by serum. 2. The known properties of the venom protease are found to be identical with those of Haas' "proinvasin I." It is concluded that the protease of the venom offers adequate explanation for the effects previously attributed to "proinvasin I." 3. Proteolytic activity is found in hyaluronidase preparations of bovine origin and is considered to be responsible for the reversal of inhibition of hyaluronidase by serum. |
format | Text |
id | pubmed-2147353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1953 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21473532008-04-23 THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE Hadidian, Z. J Gen Physiol Article 1. It has been shown that a number of proteolytic enzymes and snake venom, in relatively small amounts, and within a wide range of pH variation, will restore hyaluronidase activity after its inhibition by serum. 2. The known properties of the venom protease are found to be identical with those of Haas' "proinvasin I." It is concluded that the protease of the venom offers adequate explanation for the effects previously attributed to "proinvasin I." 3. Proteolytic activity is found in hyaluronidase preparations of bovine origin and is considered to be responsible for the reversal of inhibition of hyaluronidase by serum. The Rockefeller University Press 1953-01-20 /pmc/articles/PMC2147353/ /pubmed/13022932 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Hadidian, Z. THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE |
title | THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE |
title_full | THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE |
title_fullStr | THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE |
title_full_unstemmed | THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE |
title_short | THE ACTION OF VENOM AND PROTEOLYTIC ENZYMES ON THE NON-SPECIFIC INHIBITOR OF HYALURONIDASE |
title_sort | action of venom and proteolytic enzymes on the non-specific inhibitor of hyaluronidase |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147353/ https://www.ncbi.nlm.nih.gov/pubmed/13022932 |
work_keys_str_mv | AT hadidianz theactionofvenomandproteolyticenzymesonthenonspecificinhibitorofhyaluronidase AT hadidianz actionofvenomandproteolyticenzymesonthenonspecificinhibitorofhyaluronidase |