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OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
The polarographic current of whole blood is in excess of that given by plasma at the same oxygen tension. The magnitude of this difference depends on (a) the oxygen content of the sample and thus is determined by the red blood cell content and by the state of oxygen saturation of hemoglobin, and (b)...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1952
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147364/ https://www.ncbi.nlm.nih.gov/pubmed/13011281 |
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author | Markus, Gabor Baumberger, J. Percy |
author_facet | Markus, Gabor Baumberger, J. Percy |
author_sort | Markus, Gabor |
collection | PubMed |
description | The polarographic current of whole blood is in excess of that given by plasma at the same oxygen tension. The magnitude of this difference depends on (a) the oxygen content of the sample and thus is determined by the red blood cell content and by the state of oxygen saturation of hemoglobin, and (b) on the rate of dissociation of oxyhemoglobin and therefore is influenced by changes in pH, pCO(2), and temperature. The total current at 37°C. is proportional to the oxygen content of the sample and can be used to determine the latter. The theoretical basis of the studied phenomena is discussed in detail. |
format | Text |
id | pubmed-2147364 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1952 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21473642008-04-23 OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY Markus, Gabor Baumberger, J. Percy J Gen Physiol Article The polarographic current of whole blood is in excess of that given by plasma at the same oxygen tension. The magnitude of this difference depends on (a) the oxygen content of the sample and thus is determined by the red blood cell content and by the state of oxygen saturation of hemoglobin, and (b) on the rate of dissociation of oxyhemoglobin and therefore is influenced by changes in pH, pCO(2), and temperature. The total current at 37°C. is proportional to the oxygen content of the sample and can be used to determine the latter. The theoretical basis of the studied phenomena is discussed in detail. The Rockefeller University Press 1952-11-20 /pmc/articles/PMC2147364/ /pubmed/13011281 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Markus, Gabor Baumberger, J. Percy OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY |
title | OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY |
title_full | OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY |
title_fullStr | OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY |
title_full_unstemmed | OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY |
title_short | OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY |
title_sort | oxygen dissociation of whole blood studied polarographically |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147364/ https://www.ncbi.nlm.nih.gov/pubmed/13011281 |
work_keys_str_mv | AT markusgabor oxygendissociationofwholebloodstudiedpolarographically AT baumbergerjpercy oxygendissociationofwholebloodstudiedpolarographically |