Cargando…

OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY

The polarographic current of whole blood is in excess of that given by plasma at the same oxygen tension. The magnitude of this difference depends on (a) the oxygen content of the sample and thus is determined by the red blood cell content and by the state of oxygen saturation of hemoglobin, and (b)...

Descripción completa

Detalles Bibliográficos
Autores principales: Markus, Gabor, Baumberger, J. Percy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1952
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147364/
https://www.ncbi.nlm.nih.gov/pubmed/13011281
_version_ 1782144421952749568
author Markus, Gabor
Baumberger, J. Percy
author_facet Markus, Gabor
Baumberger, J. Percy
author_sort Markus, Gabor
collection PubMed
description The polarographic current of whole blood is in excess of that given by plasma at the same oxygen tension. The magnitude of this difference depends on (a) the oxygen content of the sample and thus is determined by the red blood cell content and by the state of oxygen saturation of hemoglobin, and (b) on the rate of dissociation of oxyhemoglobin and therefore is influenced by changes in pH, pCO(2), and temperature. The total current at 37°C. is proportional to the oxygen content of the sample and can be used to determine the latter. The theoretical basis of the studied phenomena is discussed in detail.
format Text
id pubmed-2147364
institution National Center for Biotechnology Information
language English
publishDate 1952
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21473642008-04-23 OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY Markus, Gabor Baumberger, J. Percy J Gen Physiol Article The polarographic current of whole blood is in excess of that given by plasma at the same oxygen tension. The magnitude of this difference depends on (a) the oxygen content of the sample and thus is determined by the red blood cell content and by the state of oxygen saturation of hemoglobin, and (b) on the rate of dissociation of oxyhemoglobin and therefore is influenced by changes in pH, pCO(2), and temperature. The total current at 37°C. is proportional to the oxygen content of the sample and can be used to determine the latter. The theoretical basis of the studied phenomena is discussed in detail. The Rockefeller University Press 1952-11-20 /pmc/articles/PMC2147364/ /pubmed/13011281 Text en Copyright © Copyright, 1952, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Markus, Gabor
Baumberger, J. Percy
OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
title OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
title_full OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
title_fullStr OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
title_full_unstemmed OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
title_short OXYGEN DISSOCIATION OF WHOLE BLOOD STUDIED POLAROGRAPHICALLY
title_sort oxygen dissociation of whole blood studied polarographically
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147364/
https://www.ncbi.nlm.nih.gov/pubmed/13011281
work_keys_str_mv AT markusgabor oxygendissociationofwholebloodstudiedpolarographically
AT baumbergerjpercy oxygendissociationofwholebloodstudiedpolarographically