RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER

1. The transport of sodium by frog skin and the maintenance of normal potassium levels within the cells of the skin are both dependent on metabolism and on a supply of phosphate bond energy. 2. Except for the common requirement of phosphate bond energy, the transfer mechanism for sodium and the mech...

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Detalles Bibliográficos
Autores principales: Levinsky, Norman G., Sawyer, Wilbur H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147382/
https://www.ncbi.nlm.nih.gov/pubmed/13052899
Descripción
Sumario:1. The transport of sodium by frog skin and the maintenance of normal potassium levels within the cells of the skin are both dependent on metabolism and on a supply of phosphate bond energy. 2. Except for the common requirement of phosphate bond energy, the transfer mechanism for sodium and the mechanism for maintaining intracellular potassium appear to be independent. 3. The xanthines specifically inhibit the sodium transfer mechanism; at higher concentrations, they depress metabolism and cause loss of potassium from the skin.

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