RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER

1. The transport of sodium by frog skin and the maintenance of normal potassium levels within the cells of the skin are both dependent on metabolism and on a supply of phosphate bond energy. 2. Except for the common requirement of phosphate bond energy, the transfer mechanism for sodium and the mech...

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Detalles Bibliográficos
Autores principales: Levinsky, Norman G., Sawyer, Wilbur H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147382/
https://www.ncbi.nlm.nih.gov/pubmed/13052899
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author Levinsky, Norman G.
Sawyer, Wilbur H.
author_facet Levinsky, Norman G.
Sawyer, Wilbur H.
author_sort Levinsky, Norman G.
collection PubMed
description 1. The transport of sodium by frog skin and the maintenance of normal potassium levels within the cells of the skin are both dependent on metabolism and on a supply of phosphate bond energy. 2. Except for the common requirement of phosphate bond energy, the transfer mechanism for sodium and the mechanism for maintaining intracellular potassium appear to be independent. 3. The xanthines specifically inhibit the sodium transfer mechanism; at higher concentrations, they depress metabolism and cause loss of potassium from the skin.
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spelling pubmed-21473822008-04-23 RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER Levinsky, Norman G. Sawyer, Wilbur H. J Gen Physiol Article 1. The transport of sodium by frog skin and the maintenance of normal potassium levels within the cells of the skin are both dependent on metabolism and on a supply of phosphate bond energy. 2. Except for the common requirement of phosphate bond energy, the transfer mechanism for sodium and the mechanism for maintaining intracellular potassium appear to be independent. 3. The xanthines specifically inhibit the sodium transfer mechanism; at higher concentrations, they depress metabolism and cause loss of potassium from the skin. The Rockefeller University Press 1953-05-20 /pmc/articles/PMC2147382/ /pubmed/13052899 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Levinsky, Norman G.
Sawyer, Wilbur H.
RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER
title RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER
title_full RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER
title_fullStr RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER
title_full_unstemmed RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER
title_short RELATION OF METABOLISM OF FROG SKIN TO CELLULAR INTEGRITY AND ELECTROLYTE TRANSFER
title_sort relation of metabolism of frog skin to cellular integrity and electrolyte transfer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147382/
https://www.ncbi.nlm.nih.gov/pubmed/13052899
work_keys_str_mv AT levinskynormang relationofmetabolismoffrogskintocellularintegrityandelectrolytetransfer
AT sawyerwilburh relationofmetabolismoffrogskintocellularintegrityandelectrolytetransfer

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