THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON

Decrease of the sodium concentration of the medium depresses both the spike and the associated impedance change in almost identical fashion. Elevation of the potassium level also depresses both phenomena, but affects the impedance change more than the spike; it slows the return to the initial impeda...

Descripción completa

Detalles Bibliográficos
Autores principales: Grundfest, Harry, Shanes, Abraham M., Freygang, Walter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1953
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147423/
https://www.ncbi.nlm.nih.gov/pubmed/13084889
_version_ 1782144435884130304
author Grundfest, Harry
Shanes, Abraham M.
Freygang, Walter
author_facet Grundfest, Harry
Shanes, Abraham M.
Freygang, Walter
author_sort Grundfest, Harry
collection PubMed
description Decrease of the sodium concentration of the medium depresses both the spike and the associated impedance change in almost identical fashion. Elevation of the potassium level also depresses both phenomena, but affects the impedance change more than the spike; it slows the return to the initial impedance level. The effects on the threshold to brief square waves are also described. These results appear largely accounted for by the observations of Hodgkin and Huxley with the voltage clamp technique and by their recent hypothesis as to nature of the spike processes.
format Text
id pubmed-2147423
institution National Center for Biotechnology Information
language English
publishDate 1953
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21474232008-04-23 THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON Grundfest, Harry Shanes, Abraham M. Freygang, Walter J Gen Physiol Article Decrease of the sodium concentration of the medium depresses both the spike and the associated impedance change in almost identical fashion. Elevation of the potassium level also depresses both phenomena, but affects the impedance change more than the spike; it slows the return to the initial impedance level. The effects on the threshold to brief square waves are also described. These results appear largely accounted for by the observations of Hodgkin and Huxley with the voltage clamp technique and by their recent hypothesis as to nature of the spike processes. The Rockefeller University Press 1953-09-20 /pmc/articles/PMC2147423/ /pubmed/13084889 Text en Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Grundfest, Harry
Shanes, Abraham M.
Freygang, Walter
THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON
title THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON
title_full THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON
title_fullStr THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON
title_full_unstemmed THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON
title_short THE EFFECT OF SODIUM AND POTASSIUM IONS ON THE IMPEDANCE CHANGE ACCOMPANYING THE SPIKE IN THE SQUID GIANT AXON
title_sort effect of sodium and potassium ions on the impedance change accompanying the spike in the squid giant axon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147423/
https://www.ncbi.nlm.nih.gov/pubmed/13084889
work_keys_str_mv AT grundfestharry theeffectofsodiumandpotassiumionsontheimpedancechangeaccompanyingthespikeinthesquidgiantaxon
AT shanesabrahamm theeffectofsodiumandpotassiumionsontheimpedancechangeaccompanyingthespikeinthesquidgiantaxon
AT freygangwalter theeffectofsodiumandpotassiumionsontheimpedancechangeaccompanyingthespikeinthesquidgiantaxon
AT grundfestharry effectofsodiumandpotassiumionsontheimpedancechangeaccompanyingthespikeinthesquidgiantaxon
AT shanesabrahamm effectofsodiumandpotassiumionsontheimpedancechangeaccompanyingthespikeinthesquidgiantaxon
AT freygangwalter effectofsodiumandpotassiumionsontheimpedancechangeaccompanyingthespikeinthesquidgiantaxon

Ejemplares similares