THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE

1. A procedure has been developed for the preparation of an active concentrate from the myxomycete, Physarum polycephalum. This concentrate responds with a lowered viscosity to the addition of small amounts of ATP. The preparation recovers in viscosity, and the process may be repeated. 2. In the mos...

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Detalles Bibliográficos
Autores principales: Ts'o, Paul O. P., Eggman, Luther, Vinograd, Jerome
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1956
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147562/
https://www.ncbi.nlm.nih.gov/pubmed/13319663
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author Ts'o, Paul O. P.
Eggman, Luther
Vinograd, Jerome
author_facet Ts'o, Paul O. P.
Eggman, Luther
Vinograd, Jerome
author_sort Ts'o, Paul O. P.
collection PubMed
description 1. A procedure has been developed for the preparation of an active concentrate from the myxomycete, Physarum polycephalum. This concentrate responds with a lowered viscosity to the addition of small amounts of ATP. The preparation recovers in viscosity, and the process may be repeated. 2. In the most active concentrates, 75 per cent of the non-dialyzable material moves as a single boundary both in the descending limb in electrophoresis and in the ultracentrifuge. It contains about 10 per cent ribonucleic acid, which is at least in part reversibly bound to the protein. 3. The active material has been designated myxomyosin because of its origin and its similarity to actomyosin in ATP response.
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spelling pubmed-21475622008-04-23 THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE Ts'o, Paul O. P. Eggman, Luther Vinograd, Jerome J Gen Physiol Article 1. A procedure has been developed for the preparation of an active concentrate from the myxomycete, Physarum polycephalum. This concentrate responds with a lowered viscosity to the addition of small amounts of ATP. The preparation recovers in viscosity, and the process may be repeated. 2. In the most active concentrates, 75 per cent of the non-dialyzable material moves as a single boundary both in the descending limb in electrophoresis and in the ultracentrifuge. It contains about 10 per cent ribonucleic acid, which is at least in part reversibly bound to the protein. 3. The active material has been designated myxomyosin because of its origin and its similarity to actomyosin in ATP response. The Rockefeller University Press 1956-05-20 /pmc/articles/PMC2147562/ /pubmed/13319663 Text en Copyright © Copyright, 1956, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Ts'o, Paul O. P.
Eggman, Luther
Vinograd, Jerome
THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE
title THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE
title_full THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE
title_fullStr THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE
title_full_unstemmed THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE
title_short THE ISOLATION OF MYXOMYOSIN, AN ATP-SENSITIVE PROTEIN FROM THE PLASMODIUM OF A MYXOMYCETE
title_sort isolation of myxomyosin, an atp-sensitive protein from the plasmodium of a myxomycete
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147562/
https://www.ncbi.nlm.nih.gov/pubmed/13319663
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