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Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progression

BACKGROUND: The matrix metalloproteinases (MMPs) are enzymes that cleave various components of the extracellular matrix (ECM) and basement membranes. MMPs are expressed in melanocytes and their overexpression has been linked to tumor development, progression and metastasis. At the genetic level, the...

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Detalles Bibliográficos
Autores principales:	Cotignola, Javier, Roy, Pampa, Patel, Ami, Ishill, Nicole, Shah, Shivang, Houghton, Alan, Coit, Daniel, Halpern, Allan, Busam, Klaus, Berwick, Marianne, Orlow, Irene
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148054/ https://www.ncbi.nlm.nih.gov/pubmed/17958893 http://dx.doi.org/10.1186/1477-5751-6-9

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