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ADAM15 gene structure and differential alternative exon use in human tissues

BACKGROUND: ADAM15 is a metalloprotease-disintegrin implicated in ectodomain shedding and cell adhesion. Aberrant ADAM15 expression has been associated with human cancer and other disorders. We have previously shown that the alternative splicing of ADAM15 transcripts is mis-regulated in cancer cells...

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Detalles Bibliográficos
Autores principales: Kleino, Iivari, Ortiz, Rebekka M, Huovila, Ari-Pekka J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148059/
https://www.ncbi.nlm.nih.gov/pubmed/17937806
http://dx.doi.org/10.1186/1471-2199-8-90