Cargando…
Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease
The neuronal microtubule-associated protein tau plays an important role in establishing cell polarity by stabilizing axonal microtubules that serve as tracks for motor-protein–driven transport processes. To investigate the role of tau in intracellular transport, we studied the effects of tau express...
Autores principales: | Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., Mandelkow, E.-M., Mandelkow, E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148132/ https://www.ncbi.nlm.nih.gov/pubmed/9813097 |
Ejemplares similares
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
por: Stamer, K., et al.
Publicado: (2002) -
MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
por: Mandelkow, Eva-Maria, et al.
Publicado: (2004) -
Inhibition of Tau aggregation with BSc3094 reduces Tau and decreases cognitive deficits in rTg4510 mice
por: Anglada‐Huguet, Marta, et al.
Publicado: (2021) -
Anti-aggregant tau mutant promotes neurogenesis
por: Joseph, Maria, et al.
Publicado: (2017) -
Suppressing Tau Aggregation and Toxicity by an Anti-Aggregant Tau Fragment
por: Pir, Ghulam Jeelani, et al.
Publicado: (2018)