Activation of Membrane-associated Procaspase-3 Is Regulated by Bcl-2

The mechanism by which membrane-bound Bcl-2 inhibits the activation of cytoplasmic procaspases is unknown. Here we characterize an intracellular, membrane-associated form of procaspase-3 whose activation is controlled by Bcl-2. Heavy membranes isolated from control cells contained a spontaneously ac...

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Detalles Bibliográficos
Autores principales: Krebs, Joseph F., Armstrong, Robert C., Srinivasan, Anu, Aja, Teresa, Wong, Angela M., Aboy, Aileen, Sayers, Rob, Pham, Bryan, Vu, Tam, Hoang, Kim, Karanewsky, Donald S., Leist, Christian, Schmitz, Albert, Wu, Joe C., Tomaselli, Kevin J., Fritz, Lawrence C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148187/
https://www.ncbi.nlm.nih.gov/pubmed/10085291

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