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Protein Tyrosine Phosphatase-PEST Regulates Focal Adhesion Disassembly, Migration, and Cytokinesis in Fibroblasts
In this article, we show that, in transfected COS-1 cells, protein tyrosine phosphatase (PTP)-PEST translocates to the membrane periphery following stimulation by the extracellular matrix protein fibronectin. When plated on fibronectin, PTP-PEST (−/−) fibroblasts display a strong defect in motility....
Autores principales: | Angers-Loustau, Alexandre, Côté, Jean-François, Charest, Alain, Dowbenko, Donald, Spencer, Susan, Lasky, Laurence A., Tremblay, Michel L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148201/ https://www.ncbi.nlm.nih.gov/pubmed/10085298 |
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