Cargando…

γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin

γ-Sarcoglycan is a transmembrane, dystrophin-associated protein expressed in skeletal and cardiac muscle. The murine γ-sarcoglycan gene was disrupted using homologous recombination. Mice lacking γ-sarcoglycan showed pronounced dystrophic muscle changes in early life. By 20 wk of age, these mice deve...

Descripción completa

Detalles Bibliográficos
Autores principales: Hack, Andrew A., Ly, Chantal T., Jiang, Fang, Clendenin, Cynthia J., Sigrist, Kirsten S., Wollmann, Robert L., McNally, Elizabeth M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149352/
https://www.ncbi.nlm.nih.gov/pubmed/9732288

Ejemplares similares