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Exploiting tumour hypoxia and overcoming mutant p53 with tirapazamine.
Human solid tumours are composed of a significant proportion of hypoxic cells, i.e. cells with oxygen levels lower than those of normal tissues. Tumour hypoxic cells have been shown to have a negative impact on the response of solid tumours to radiation therapy and chemotherapy. However, these low c...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149884/ https://www.ncbi.nlm.nih.gov/pubmed/9647614 |