p53 mutation is a poor prognostic indicator for survival in patients with hepatocellular carcinoma undergoing surgical tumour ablation.

Forty-two patients with hepatocellular carcinoma (HCC) were resected and their tumours were analysed for p53 mutations by GC-clamped denaturing gradient gel electrophoresis (DGGE), single-strand conformation polymorphism (SSCP) and gene sequencing. All the exons have been analysed in this study. Eig...

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Detalles Bibliográficos
Autores principales: Honda, K., Sbisà, E., Tullo, A., Papeo, P. A., Saccone, C., Poole, S., Pignatelli, M., Mitry, R. R., Ding, S., Isla, A., Davies, A., Habib, N. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149958/
https://www.ncbi.nlm.nih.gov/pubmed/9514057

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