Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer.

Poly(ADP-ribose)polymerase (PARP) has been implicated in DNA repair mechanisms and the associated activity shown to markedly increase after DNA damage in carcinogen-treated cells. A defective DNA repair has been associated to the aetiology of human cancers. In order to assess the potential role of t...

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Detalles Bibliográficos
Autores principales: Cristóvão, L., Lechner, M. C., Fidalgo, P., Leitão, C. N., Mira, F. C., Rueff, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150072/
https://www.ncbi.nlm.nih.gov/pubmed/9635838

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