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Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.

To investigate the possible dependence of 5-fluorouracil (5FU) uptake in tumours on the intra- (pHi) and extracellular (pHe) pH, a pH gradient (deltapH) was imposed across the plasma membrane of ascites tumour cells in vitro, similar to that known to occur in some solid tumours in vivo, by incubatio...

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Detalles Bibliográficos
Autores principales:	Ojugo, A. S., McSheehy, P. M., Stubbs, M., Alder, G., Bashford, C. L., Maxwell, R. J., Leach, M. O., Judson, I. R., Griffiths, J. R.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1998
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150086/ https://www.ncbi.nlm.nih.gov/pubmed/9528827

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