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The pharmacokinetics and metabolism of ifosfamide during bolus and infusional administration: a randomized cross-over study.
In a randomized cross-over trial, 11 patients received ifosfamide (IFOS) in 21-day cycles, which alternated between 3 g m(-2) x (2 or 3) days given as a 1-h bolus doses, or the same total dose as a continuous infusion. Patients who received four or more cycles also alternated between two cycles on d...
Autores principales: | Singer, J. M., Hartley, J. M., Brennan, C., Nicholson, P. W., Souhami, R. L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150089/ https://www.ncbi.nlm.nih.gov/pubmed/9528844 |
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