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Raltitrexed (Tomudex): an alternative drug for patients with colorectal cancer and 5-fluorouracil associated cardiotoxicity.
Two patients with proven 5-fluorouracil (5-FU)-associated cardiotoxicity were treated with the specific thymidylate synthase inhibitor raltitrexed safely, without evidence of cardiotoxicity. Raltitrexed might be an alternative for patients with advanced colorectal cancer and 5-FU-associated cardioto...
Autores principales: | Köhne, C. H., Thuss-Patience, P., Friedrich, M., Daniel, P. T., Kretzschmar, A., Benter, T., Bauer, B., Dietz, R., Dörken, B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150099/ https://www.ncbi.nlm.nih.gov/pubmed/9528843 |
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