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Phase II trial of dexverapamil and epirubicin in patients with non-responsive metastatic breast cancer.
Agents capable of reversing P-glycoprotein-associated multidrug resistance have usually failed to enhance chemotherapy activity in patients with solid tumours. Based on its toxicity profile and experimental potency, dexverapamil, the R-enantiomer of verapamil, is considered to be promising for clini...
Autores principales: | Lehnert, M., Mross, K., Schueller, J., Thuerlimann, B., Kroeger, N., Kupper, H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150143/ https://www.ncbi.nlm.nih.gov/pubmed/9569055 |
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