Down-regulation of Fas gene expression in colon cancer is not a result of allelic loss or gene rearrangement.

Expression of Fas, an apoptosis-inducing receptor, in colonic epithelium is progressively reduced during malignant transformation. We have examined the human Fas gene for loss of heterozygosity (LOH) and gross rearrangements in colon tumours and matched normal mucosa. Polymerase chain reaction (PCR)...

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Detalles Bibliográficos
Autores principales: Butler, L. M., Hewett, P. J., Butler, W. J., Cowled, P. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150190/
https://www.ncbi.nlm.nih.gov/pubmed/9652761

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