Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.

Tumour S-phase fraction, but not the apoptotic fraction, had prognostic value in 92 patients with B-cell non-Hodgkin's lymphoma (P < 0.0001 and P = 0.85 respectively). Multivariate analysis showed that S-phase fraction was the strongest prognostic indicator in all cases (P = 0.0003, relative...

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Autores principales: Stokke, T., Smeland, E. B., Kvaløy, S., Holte, H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150310/
https://www.ncbi.nlm.nih.gov/pubmed/9667655
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author Stokke, T.
Smeland, E. B.
Kvaløy, S.
Holte, H.
author_facet Stokke, T.
Smeland, E. B.
Kvaløy, S.
Holte, H.
author_sort Stokke, T.
collection PubMed
description Tumour S-phase fraction, but not the apoptotic fraction, had prognostic value in 92 patients with B-cell non-Hodgkin's lymphoma (P < 0.0001 and P = 0.85 respectively). Multivariate analysis showed that S-phase fraction was the strongest prognostic indicator in all cases (P = 0.0003, relative risk 4.3; age: P = 0.16; grade: P = 0.81), as well as in the 63 primary biopsy cases (P = 0.0006, relative risk = 7.3; international prognostic index: P = 0.015, relative risk = 3.2; B symptoms: P = 0.017, relative risk = 3.3; bulkiness: P = 0.65; grade: P = 0.91).
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spelling pubmed-21503102009-09-10 Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas. Stokke, T. Smeland, E. B. Kvaløy, S. Holte, H. Br J Cancer Research Article Tumour S-phase fraction, but not the apoptotic fraction, had prognostic value in 92 patients with B-cell non-Hodgkin's lymphoma (P < 0.0001 and P = 0.85 respectively). Multivariate analysis showed that S-phase fraction was the strongest prognostic indicator in all cases (P = 0.0003, relative risk 4.3; age: P = 0.16; grade: P = 0.81), as well as in the 63 primary biopsy cases (P = 0.0006, relative risk = 7.3; international prognostic index: P = 0.015, relative risk = 3.2; B symptoms: P = 0.017, relative risk = 3.3; bulkiness: P = 0.65; grade: P = 0.91). Nature Publishing Group 1998-06 /pmc/articles/PMC2150310/ /pubmed/9667655 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Stokke, T.
Smeland, E. B.
Kvaløy, S.
Holte, H.
Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.
title Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.
title_full Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.
title_fullStr Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.
title_full_unstemmed Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.
title_short Tumour cell proliferation, but not apoptosis, predicts survival in B-cell non-Hodgkin's lymphomas.
title_sort tumour cell proliferation, but not apoptosis, predicts survival in b-cell non-hodgkin's lymphomas.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150310/
https://www.ncbi.nlm.nih.gov/pubmed/9667655
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