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Cyclophosphamide, methotrexate and infusional 5-fluorouracil (infusional CMF) in metastatic breast cancer.
Bolus 5-fluorouracil (5-FU) is a phase-specific drug with a short plasma half-life that is used in combination with bolus cyclophosphamide and methotrexate in the treatment of breast cancer. The efficacy of 5-FU can be improved by continuous intravenous infusion using portable infusion pumps (infusi...
Autores principales: | O'Byrne, K. J., Koukourakis, M. I., Saunders, M. P., Salisbury, A. J., Isaacs, R., Varcoe, S., Taylor, M., Ganesan, T. S., Harris, A. L., Talbot, D. C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150339/ https://www.ncbi.nlm.nih.gov/pubmed/9667673 |
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