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Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours.
The poor blood supply to solid tumours introduces many factors that affect the outcome of chemotherapy, one of which is the problem of drug delivery to poorly vascularized regions of tumours. Whereas poor drug penetration has been recognized as a contributing factor to the poor response of many soli...
Autores principales: | Phillips, R. M., Loadman, P. M., Cronin, B. P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150429/ https://www.ncbi.nlm.nih.gov/pubmed/9649122 |
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