Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

Targeted disruption of core binding factor α1 (Cbfa1) showed that Cbfa1 is an essential transcription factor in osteoblast differentiation and bone formation. Furthermore, both in vitro and in vivo studies showed that Cbfa1 plays important roles in matrix production and mineralization. However, it r...

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Detalles Bibliográficos
Autores principales: Liu, Wenguang, Toyosawa, Satoru, Furuichi, Tatsuya, Kanatani, Naoko, Yoshida, Carolina, Liu, Yang, Himeno, Miki, Narai, Satoru, Yamaguchi, Akira, Komori, Toshihisa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150799/
https://www.ncbi.nlm.nih.gov/pubmed/11581292
http://dx.doi.org/10.1083/jcb.200105052

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