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Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
Formation of the immunological synapse (IS) in T cells involves large scale molecular movements that are mediated, at least in part, by reorganization of the actin cytoskeleton. Various signaling proteins accumulate at the IS and are localized in specialized membrane microdomains, known as lipid raf...
Autores principales: | Villalba, Martin, Bi, Kun, Rodriguez, Fernando, Tanaka, Yoshihiko, Schoenberger, Stephen, Altman, Amnon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150846/ https://www.ncbi.nlm.nih.gov/pubmed/11684704 http://dx.doi.org/10.1083/jcb.200107080 |
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