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Keratin attenuates tumor necrosis factor–induced cytotoxicity through association with TRADD

Keratin 8 and 18 (K8/18) are the major components of intermediate filament (IF) proteins of simple or single-layered epithelia. Recent data show that normal and malignant epithelial cells deficient in K8/18 are nearly 100 times more sensitive to tumor necrosis factor (TNF)–induced cell death. We hav...

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Detalles Bibliográficos
Autores principales:	Inada, Hiroyasu, Izawa, Ichiro, Nishizawa, Miwako, Fujita, Eriko, Kiyono, Tohru, Takahashi, Toshitada, Momoi, Takashi, Inagaki, Masaki
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150850/ https://www.ncbi.nlm.nih.gov/pubmed/11684708 http://dx.doi.org/10.1083/jcb.200103078

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