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Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding
Proteins destined for the secretory pathway must first fold and assemble in the lumen of endoplasmic reticulum (ER). The pathway maintains a quality control mechanism to assure that aberrantly processed proteins are not delivered to their sites of function. As part of this mechanism, misfolded prote...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150856/ https://www.ncbi.nlm.nih.gov/pubmed/11673477 http://dx.doi.org/10.1083/jcb.200106123 |