Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition

FGF signaling uses receptor tyrosine kinases that form high-affinity complexes with FGFs and heparan sulfate (HS) proteoglycans at the cell surface. It is hypothesized that assembly of these complexes requires simultaneous recognition of distinct sulfation patterns within the HS chain by FGF and the...

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Detalles Bibliográficos
Autores principales: Allen, Benjamin L., Filla, Mark S., Rapraeger, Alan C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150861/
https://www.ncbi.nlm.nih.gov/pubmed/11724824
http://dx.doi.org/10.1083/jcb.200106075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150861/
https://www.ncbi.nlm.nih.gov/pubmed/11724824
http://dx.doi.org/10.1083/jcb.200106075

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