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Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition
FGF signaling uses receptor tyrosine kinases that form high-affinity complexes with FGFs and heparan sulfate (HS) proteoglycans at the cell surface. It is hypothesized that assembly of these complexes requires simultaneous recognition of distinct sulfation patterns within the HS chain by FGF and the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150861/ https://www.ncbi.nlm.nih.gov/pubmed/11724824 http://dx.doi.org/10.1083/jcb.200106075 |