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The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro
Keratin filaments arise from the copolymerization of type I and II sequences, and form a pancytoplasmic network that provides vital mechanical support to epithelial cells. Keratins 5 and 14 are expressed as a pair in basal cells of stratified epithelia, where they occur as bundled arrays of filament...
Autores principales: | Bousquet, Olivier, Ma, Linglei, Yamada, Soichiro, Gu, Changhong, Idei, Toshihiro, Takahashi, Kenzo, Wirtz, Denis, Coulombe, Pierre A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150872/ https://www.ncbi.nlm.nih.gov/pubmed/11724817 http://dx.doi.org/10.1083/jcb.200104063 |
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