Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

CD44 is a widely distributed cell surface adhesion molecule and is implicated in diverse biological processes. However, the nature of intracellular signaling triggered by CD44 remains to be elucidated. Here, we show that CD44 undergoes sequential proteolytic cleavage in the ectodomain and intracellu...

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Detalles Bibliográficos
Autores principales: Okamoto, Isamu, Kawano, Yoshiaki, Murakami, Daizo, Sasayama, Takashi, Araki, Norie, Miki, Toru, Wong, Albert J., Saya, Hideyuki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150876/
https://www.ncbi.nlm.nih.gov/pubmed/11714729
http://dx.doi.org/10.1083/jcb.200108159

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