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The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling

Inhibitory Smads (I-Smads) repress signaling by cytokines of the transforming growth factor-β (TGF-β) superfamily. I-Smads have conserved carboxy-terminal Mad homology 2 (MH2) domains, whereas the amino acid sequences of their amino-terminal regions (N domains) are highly divergent from those of oth...

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Detalles Bibliográficos
Autores principales:	Hanyu, Aki, Ishidou, Yasuhiro, Ebisawa, Takanori, Shimanuki, Tomomasa, Imamura, Takeshi, Miyazono, Kohei
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150897/ https://www.ncbi.nlm.nih.gov/pubmed/11739411 http://dx.doi.org/10.1083/jcb.200106023

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