Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH(2) terminus in ER export

The Sar1 GTPase is an essential component of COPII vesicle coats involved in export of cargo from the ER. We report the 1.7-Å structure of Sar1 and find that consistent with the sequence divergence of Sar1 from Arf family GTPases, Sar1 is structurally distinct. In particular, we show that the Sar1 N...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Mingdong, Weissman, Jacques T., Béraud-Dufour, Sophie, Luan, Peng, Wang, Chenqian, Chen, Wei, Aridor, Meir, Wilson, Ian A., Balch, William E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150902/
https://www.ncbi.nlm.nih.gov/pubmed/11739406
http://dx.doi.org/10.1083/jcb.200106039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150902/
https://www.ncbi.nlm.nih.gov/pubmed/11739406
http://dx.doi.org/10.1083/jcb.200106039

Ejemplares similares