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Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH(2) terminus in ER export
The Sar1 GTPase is an essential component of COPII vesicle coats involved in export of cargo from the ER. We report the 1.7-Å structure of Sar1 and find that consistent with the sequence divergence of Sar1 from Arf family GTPases, Sar1 is structurally distinct. In particular, we show that the Sar1 N...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150902/ https://www.ncbi.nlm.nih.gov/pubmed/11739406 http://dx.doi.org/10.1083/jcb.200106039 |