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Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
Axin is a component of the canonical Wnt pathway that negatively regulates signal transduction by promoting degradation of β-catenin. To study the role of Axin in development, we developed strains of transgenic mice in which its expression can be manipulated by the administration of doxycycline (Dox...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150907/ https://www.ncbi.nlm.nih.gov/pubmed/11739413 http://dx.doi.org/10.1083/jcb.200107066 |