Constructing a Golgi complex

In this issue, Short et al. report the discovery of a protein named Golgin-45 that is located on the surface of the middle (or medial) cisternae of the Golgi complex. Depletion of this protein disrupts the Golgi complex and leads to the return of a resident, lumenal, medial Golgi enzyme to the endop...

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Detalles Bibliográficos
Autor principal: Pfeffer, Suzanne R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150916/
https://www.ncbi.nlm.nih.gov/pubmed/11739400
http://dx.doi.org/10.1083/jcb.200109095
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author Pfeffer, Suzanne R.
author_facet Pfeffer, Suzanne R.
author_sort Pfeffer, Suzanne R.
collection PubMed
description In this issue, Short et al. report the discovery of a protein named Golgin-45 that is located on the surface of the middle (or medial) cisternae of the Golgi complex. Depletion of this protein disrupts the Golgi complex and leads to the return of a resident, lumenal, medial Golgi enzyme to the endoplasmic reticulum. These findings suggest that Golgin-45 serves as a linchpin for the maintenance of Golgi complex structure, and offer hints as to the mechanisms by which the polarized Golgi complex is constructed.
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spelling pubmed-21509162008-05-01 Constructing a Golgi complex Pfeffer, Suzanne R. J Cell Biol Comment In this issue, Short et al. report the discovery of a protein named Golgin-45 that is located on the surface of the middle (or medial) cisternae of the Golgi complex. Depletion of this protein disrupts the Golgi complex and leads to the return of a resident, lumenal, medial Golgi enzyme to the endoplasmic reticulum. These findings suggest that Golgin-45 serves as a linchpin for the maintenance of Golgi complex structure, and offer hints as to the mechanisms by which the polarized Golgi complex is constructed. The Rockefeller University Press 2001-12-10 /pmc/articles/PMC2150916/ /pubmed/11739400 http://dx.doi.org/10.1083/jcb.200109095 Text en Copyright © 2001, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Comment
Pfeffer, Suzanne R.
Constructing a Golgi complex
title Constructing a Golgi complex
title_full Constructing a Golgi complex
title_fullStr Constructing a Golgi complex
title_full_unstemmed Constructing a Golgi complex
title_short Constructing a Golgi complex
title_sort constructing a golgi complex
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150916/
https://www.ncbi.nlm.nih.gov/pubmed/11739400
http://dx.doi.org/10.1083/jcb.200109095
work_keys_str_mv AT pfeffersuzanner constructingagolgicomplex

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