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Broad phase II and pharmacokinetic study of methoxy-morpholino doxorubicin (FCE 23762-MMRDX) in non-small-cell lung cancer, renal cancer and other solid tumour patients.
The aim was to perform a broad phase II and pharmacokinetic study of methoxymorpholino-doxorubicin (MMRDX), a drug active against multidrug-resistant tumour cells in vitro when given by i.v. bolus at 1.5 mg m(-2) every 4 weeks, in metastatic or unresectable solid tumour patients with known intrinsic...
Autores principales: | Bakker, M., Droz, J. P., Hanauske, A. R., Verweij, J., van Oosterom, A. T., Groen, H. J., Pacciarini, M. A., Domenigoni, L., van Weissenbruch, F., Pianezzola, E., de Vries, E. G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151269/ https://www.ncbi.nlm.nih.gov/pubmed/9459159 |
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