Single-channel Properties of Human Na(V)1.1 and Mechanism of Channel Dysfunction in SCN1A-associated Epilepsy

Mutations in genes encoding neuronal voltage-gated sodium channel subunits have been linked to inherited forms of epilepsy. The majority of mutations (>100) associated with generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epilepsy of infancy (SMEI) occur in SCN1A encod...

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Detalles Bibliográficos
Autores principales: Vanoye, Carlos G., Lossin, Christoph, Rhodes, Thomas H., George, Alfred L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151481/
https://www.ncbi.nlm.nih.gov/pubmed/16380441
http://dx.doi.org/10.1085/jgp.200509373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151481/
https://www.ncbi.nlm.nih.gov/pubmed/16380441
http://dx.doi.org/10.1085/jgp.200509373

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