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Effects of Multiple Metal Binding Sites on Calcium and Magnesium-dependent Activation of BK Channels
BK channels are activated by physiological concentrations of intracellular Ca(2+) and Mg(2+) in a variety of cells. Previous studies have identified two sites important for high-affinity Ca(2+) sensing between [Ca(2+)](i) of 0.1–100 μM and a site important for Mg(2+) sensing between [Mg(2+)](i) of 0...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151482/ https://www.ncbi.nlm.nih.gov/pubmed/16344323 http://dx.doi.org/10.1085/jgp.200509317 |