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Role of Charged Residues in the S1–S4 Voltage Sensor of BK Channels

The activation of large conductance Ca(2+)-activated (BK) potassium channels is weakly voltage dependent compared to Shaker and other voltage-gated K(+) (K(V)) channels. Yet BK and K(V) channels share many conserved charged residues in transmembrane segments S1–S4. We mutated these residues individu...

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Detalles Bibliográficos
Autores principales: Ma, Zhongming, Lou, Xing Jian, Horrigan, Frank T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151507/
https://www.ncbi.nlm.nih.gov/pubmed/16505150
http://dx.doi.org/10.1085/jgp.200509421

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