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Role of Charged Residues in the S1–S4 Voltage Sensor of BK Channels
The activation of large conductance Ca(2+)-activated (BK) potassium channels is weakly voltage dependent compared to Shaker and other voltage-gated K(+) (K(V)) channels. Yet BK and K(V) channels share many conserved charged residues in transmembrane segments S1–S4. We mutated these residues individu...
Autores principales: | Ma, Zhongming, Lou, Xing Jian, Horrigan, Frank T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151507/ https://www.ncbi.nlm.nih.gov/pubmed/16505150 http://dx.doi.org/10.1085/jgp.200509421 |
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