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Soluble Amyloid Oligomers Increase Bilayer Conductance by Altering Dielectric Structure
The amyloid hypothesis of Alzheimer's toxicity has undergone a resurgence with increasing evidence that it is not amyloid fibrils but a smaller oligomeric species that produces the deleterious results. In this paper we address the mechanism of this toxicity. Only oligomers increase the conducta...
Autores principales: | Sokolov, Yuri, Kozak, J. Ashot, Kayed, Rakez, Chanturiya, Alexandr, Glabe, Charles, Hall, James E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151594/ https://www.ncbi.nlm.nih.gov/pubmed/17101816 http://dx.doi.org/10.1085/jgp.200609533 |
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