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Secondary Structure of a KCNE Cytoplasmic Domain

Type I transmembrane KCNE peptides contain a conserved C-terminal cytoplasmic domain that abuts the transmembrane segment. In KCNE1, this region is required for modulation of KCNQ1 K(+) channels to afford the slowly activating cardiac I(Ks) current. We utilized alanine/leucine scanning to determine...

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Detalles Bibliográficos
Autores principales:	Rocheleau, Jessica M., Gage, Steven D., Kobertz, William R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151597/ https://www.ncbi.nlm.nih.gov/pubmed/17130521 http://dx.doi.org/10.1085/jgp.200609657

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