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Structural Determinants of the Closed KCa3.1 Channel Pore in Relation to Channel Gating: Results from a Substituted Cysteine Accessibility Analysis

In this work we address the question of the KCa3.1 channel pore structure in the closed configuration in relation to the contribution of the C-terminal end of the S6 segments to the Ca(2+)-dependent gating process. Our results based on SCAM (substituted cysteine accessibility method) experiments fir...

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Detalles Bibliográficos
Autores principales:	Klein, Hélène, Garneau, Line, Banderali, Umberto, Simoes, Manuel, Parent, Lucie, Sauvé, Rémy
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151617/ https://www.ncbi.nlm.nih.gov/pubmed/17353352 http://dx.doi.org/10.1085/jgp.200609726

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