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Control of Inward Rectifier K Channel Activity by Lipid Tethering of Cytoplasmic Domains
Interactions between nontransmembrane domains and the lipid membrane are proposed to modulate activity of many ion channels. In Kir channels, the so-called “slide-helix” is proposed to interact with the lipid headgroups and control channel gating. We examined this possibility directly in a cell-free...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151642/ https://www.ncbi.nlm.nih.gov/pubmed/17698595 http://dx.doi.org/10.1085/jgp.200709764 |