Could pharmacogenetic data explain part of the interindividual sensitivity to methadone-induced respiratory depression?

In this issue of Critical Care, Megarbane and colleagues present a case report of methadone-induced respiratory depression and conduct a toxicokinetic/toxicodynamic evaluation. An opioid-dependent patient receiving methadone maintenance treatment (daily dose 70 mg) was found unconscious after ingest...

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Detalles Bibliográficos
Autores principales: Crettol, Séverine, Monnat, Martine, Eap, Chin B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151888/
https://www.ncbi.nlm.nih.gov/pubmed/17338832
http://dx.doi.org/10.1186/cc5699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151888/
https://www.ncbi.nlm.nih.gov/pubmed/17338832
http://dx.doi.org/10.1186/cc5699

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